Returned with those skills to Okinawa

Group II introns are a large class of self-catalytic ribozymes and mobile genetic elements found within the genes of all three domains of life. Ribozyme activity can occur under high-salt conditions in vitro. However, assistance from proteins is required for in vivo splicing. In contrast to group I introns, intron excision occurs in the absence of GTP and involves the formation of a lariat, with an A-residue branchpoint strongly resembling that found in lariats formed during splicing of nuclear pre-mRNA. It is hypothesized that pre-mRNA splicing may have evolved from group II introns, due to the similar catalytic mechanism as well as the structural similarity of the Group II Domain V substructure to the U6/U2 extended snRNA. Finally, their ability to site-specifically insert into DNA sites has been exploited as a tool for biotechnology. For example, group II introns can be modified to make site-specific genome insertions and deliver cargo DNA such as reporter genes or lox sites

Higaonna Kanryō , and sometimes known as Higashionna West to distinguish him from his cousin, was a Ryukyuan martial artist who founded a fighting style known at the time as Naha-te. He is recognized as one of the first students of Fujian White Crane Kung Fu masters, namely Ryū Ryū Ko, in the Fuzhou region of China who returned with those skills to Okinawa. His student, Chōjun Miyagi, would later found Gōjū ryū Karate.